The chief pathologic features of osteoarthritis are a. autoimmune damage to the synovium, destruction of articular cartilage by pannus, and thickening of synovial fluid. b. thinning of the joint capsule, resorption of bone, excessive formation of new bone, and formation of bone spurs. c. degeneration of articular cartilage, destruction of the bone under the cartilage, and thickening of the synovium. d. stress fractures of the epiphysis, inflammation of the diaphysis, and accumulation of excessive synovial fluid.

Osteoarthritis may be defined as the one of the most common form of arthritis that affects the joints of knees and hands. The symptoms of arthritis are stiffness, pain and loss of flexibility.

The articular cartilage get degenerated, thickening of synovium and the breakage of bone under the cartilage. Maintenance of healthy weight and proper treatment can reduce the risk of disease.

Thus, the correct answer is option (C).