Rett syndrome is an X-linked dominant disorder that means a dominant allele is required to affect the individual, but this condition is not applied to females.
What do you mean by Allele?
An Allele may be defined as one or two or more alternate forms of a particular gene.
In Rett syndrome, Females require both the dominant form of alleles to cause the disorder i.e. [tex]X^HX^H[/tex], while [tex]X^HX^h[/tex] is a condition of carrier females.
In the case of males, there is only one X-chromosome, so only one dominant allele is sufficient to cause the disorder i.e. [tex]X^HY[/tex].
Therefore, it is well described. To understand more, refer to the Punnett square given below.
To learn more about X-linked dominant disorder, refer to the link:
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