Assuming that the disease decreases the affected component: Osteocytes: These help in bone production so if they decrease, bone density will decrease. Osteoclasts: These break bone down so if they decrease, bone density increases Osteoblasts: Help in bone production, their decrease will reduce bone density. Collagen fibers: Help in bone production, their decrease will reduce bone density.
The disease of osteocytes, osteoclasts, osteoblasts, and collagen fibers would affect bone density by causing a weakening of the bones. With bone density weakened, it leaves bones susceptible to breakage.
