HELP PLEASE ! 100 POINTS !

Five strands of mRNA are depicted here, numbered 1-5. The mRNA sequence labeled number
1 indicates the codons that result from the transcription of the original, unmutated DNA. Identify
the statements below that accurately describe the impacts of the mutations shown based on the
illustrations. Select ALL THREE answer choices that apply.

A). 2 is a silent mutation since the same number of codons are being coded for, resulting in a
protein with intact functionality.

B). 3 is the single nucleotide deletion, which causes a frameshift in the codons. The protein's
function is significantly altered.

C). 3 and 4 are missense mutations, with only single changes to the genome that result in single
changes to the protein, whose function is intact.

D).4 is the nucleotide insertion, resulting in a frameshift mutation. The protein's function is
significantly altered.

E). 5 is codon duplication, with three additional bases, which can result in a protein with
significant functionality changes.

The statement '3 is the single nucleotide deletion, which causes a frameshift in the codons. The protein's function is significantly altered' is correct.

What is a mutation?

A mutation is a genetic change in the nucleotide sequence, which can be used to encode a protein.

A mutation deletion is the loss of one or more nucleotides of the original sequence, which changes the open reading frame (ORF) of the resulting protein.

A synonymous mutation is a nucleotide modification that doesn't change the amino acid that will be added to the protein during translation.

In conclusion, the statement '3 is the single nucleotide deletion, which causes a frameshift in the codons. The protein's function is significantly altered' is correct (the remaining statements are false or the information is incomplete).

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