Local effects from chemical exposure occur:
Systemic effects from chemical exposure occur:
The degree to which a chemical compound or a certain combination of chemicals can harm an organism is known as its toxicity. Toxicity can refer to an impact on an entire organism, such as an animal, bacteria, or plant, as well as an impact on an organism's cell structure or an organ, such as the liver.
Systemic effects are those that manifest in tissues that are not in close proximity to the site of interaction between the body and the medical device or biomaterial.
Regardless of whether a chemical is systemically available, a local effect is one that is seen at the point of first contact.
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