Which of the following statements help to explain the pathogenesis of human transmissible spongiform encephalopathy?
a) The shape of normal host PrpC protein is altered by abnormal PrpSc protein, transforming it into infectious PrpSc protein.
b) The expression of the host-normal prpC gene is enhanced by the PrpSc activator protein.
c) Host PrpC protein is hydrolyzed by PrpSc protein into smaller, nonfunctional particles, which are eventually degraded by the cell's proteasome.
d) The expression of the host-normal prpC gene is blocked by the PrpSc repressor protein

Question

drewefielder8443 drewefielder8443

12-12-2022
Biology

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Which of the following statements help to explain the pathogenesis of human transmissible spongiform encephalopathy?
a) The shape of normal host PrpC protein is altered by abnormal PrpSc protein, transforming it into infectious PrpSc protein.
b) The expression of the host-normal prpC gene is enhanced by the PrpSc activator protein.
c) Host PrpC protein is hydrolyzed by PrpSc protein into smaller, nonfunctional particles, which are eventually degraded by the cell's proteasome.
d) The expression of the host-normal prpC gene is blocked by the PrpSc repressor protein

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Yakavi Yakavi · Answer 1 · 2022-12-16T19:10:43+01:00

The shape of normal host PrpC protein is altered by abnormal PrpSc protein, transforming it into infectious PrpSc protein this statement contributes to understanding the pathogenesis of human transmissible spongiform encephalopathy.

Pathogenesis refers to the sequence of events that occurs during acute and chronic infections. It consists of the virus entering the body, multiplying and spreading, causing tissue damage, and producing an immune response, which may contribute to the pathology of an infection.

Pathogenesis can take many forms, including microbial infection, inflammation, cancer, and tissue breakdown. For instance, bacterial pathogenesis is indeed the process whereby bacteria end up causing infectious illness. Most diseases have been caused by a combination of factors.

BSE (bovine spongiform encephalopathy) is indeed a progressive neurological disorder caused by an unusual transmissible agent known as a prion. The nature of both the transmissible agent is unknown.

To know more about the Encephalopathy, here

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